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Sources of Oxidized Cholesterol | NutritionFacts.org

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Chicken, fish, and egg powder in processed meals current higher threat from ldl cholesterol oxidation byproducts, however there are issues you are able to do to cut back publicity.

“A significant body of evidence indicates that oxidized cholesterol, in the form of oxysterols, is one of the main triggers of AD [Alzheimer’s disease].” But, that’s not all. Cholesterol oxidation merchandise (COPs) “are associated with the initiation and progression of major chronic diseases,” together with coronary heart illness, diabetes, and kidney failure. COPs are produced when animal merchandise are heated. All kinds of cooking can do it, since you may get “maximum cholesterol oxidation and COP production” at solely about 300 levels Fahrenheit, however are there any varieties of cooking which can be worse than others? As I focus on in my video How to Reduce Cholesterol Oxidation, in case you look at “foal meat”—child horse meat—greater ranges of oxidation on the whole had been present in microwaved meat, as you’ll be able to see at 0:40 within the video.

Indeed, microwaving hen or beef appears to provide about twice as a lot ldl cholesterol oxidation as does frying. If you look at bacon, although, uncooked bacon didn’t have any oxidized ldl cholesterol. Like all animal merchandise, it has ldl cholesterol, but it surely’s not oxidized till you prepare dinner it. Grilling appears to be the most secure in case you eat the meat immediately, however in case you put leftovers within the fridge and reheat them later utilizing the identical technique, all of the oxidized levels of cholesterol shoot up, as you’ll be able to see at 0:58 in my video.

It’s not simply warmth, although. Although ranges in uncooked meats are normally low, “their concentrations tend to increase dramatically after exposure to proxidant [or, pro-oxidation] agents such as light.” Okay, but it surely isn’t like you’ll be able to crawl contained in the pig and eat bacon from the within. Isn’t meat all the time uncovered to mild? Well, however you would wrap the meat in pink plastic wrap. Clear plastic wrap doesn’t appear to work, however pink movie blocks some of the sunshine waves and might delay ldl cholesterol oxidation—at the very least it labored for “horse meat slices.” The drawback is worse with sliced meat merchandise, as a result of extra of the meat is exposed to air and light-weight. It’s the identical with floor meat—it’s simply a lot extra exposed.

Unless you keep meat in some sort of vacuum pack, the oxygen publicity alone can shoot up oxidation ranges even in a darkish fridge or the freezer. As you’ll be able to see at 2:04 in my video, cooking uncooked fish can boost ldl cholesterol oxides ranges from 8 μg/g to 18 μg/g, however, after a couple of months, frozen fish—even frozen uncooked fish—begins out about ten instances greater and simply goes up from there.

In phrases of which meat is the worst, hen was twice as dangerous as beef, whether or not microwaved or fried. It appears the explanation has to do with the polyunsaturated fats content material of the muscle, which “decreases in the order fish [with the highest content] > poultry > pork > beef > lamb.” So, chicken is extra vulnerable to ldl cholesterol oxidation. Red meat has extra saturated fats, however fish and hen have a tendency to construct up extra oxidized ldl cholesterol. So, hen and roasted salmon have been shown to generate higher quantities of ldl cholesterol oxidation merchandise than different varieties of meat. Surprisingly, although, the very best enhance of oxidized ldl cholesterol in salmon was found by way of steaming, primarily as a result of it’s simply uncovered to warmth longer. Cholesterol oxidation elevated after every cooking process, however “steaming increased the total amount by more than 1000%.”

There are two methods hen meat might pull forward, although. One is in case you feed the chickens rancid fats. Unfortunately, all method of substandard “fat by- and coproducts” might end up on the rendering crops to be changed into animal feed. The second means is irradiation. As you’ll be able to see at 3:28 in my video, when hen meat is irradiated to enhance its meals security from an infectious illness standpoint, it could diminish meals security from a persistent illness standpoint—however, hey, It’s higher than dying from Salmonella.

In phrases of dairy, it’s possible you’ll recall that I talked concerning the potential risks of ghee in my video Oxidized Cholesterol as a Cause of Alzheimer’s Disease, which made me marvel about UHT milk. UHT stands for ultra-high temperature processing. It’s used to make these little Half & Half “no refrigeration needed” espresso creamers. As you’ll be able to see at 4:00 in my video, UHT seems to boost oxidized levels of cholesterol by about 50 %, which is greater than common pasteurization. Interestingly, nonetheless, if you’ll find goat milk Half & Half, that might be safer.

Same drawback with eggs. Egg powder in processed meals is good for shelf life, but it surely will not be so good for human life. Some examples of packaged meals with egg merchandise include some pastas, many baked items, and mayonnaise. So, even individuals who keep away from eggs out of the egg carton should still be uncovered unwittingly by way of processed meals in the event that they don’t learn the elements label.

If it’s all about oxidation, why not simply add artificial or pure antioxidants to the animal merchandise themselves? The meat business has definitely tried—for example, adding lemon balm tea to hamburger patties. It didn’t work, however that’s doubtless as a result of they couldn’t add sufficient with out affecting the style. What about including cherries? They’re pink, so they’d mix proper in. As you’ll be able to see at 5:00 in my video, cherries worked! Two differing kinds of tart cherries considerably lowered the ldl cholesterol oxidation, however meat with a cherry on high appears somewhat odd. How about simply good previous garlic and onions? The quantity of oxidized ldl cholesterol in a plain pork chop considerably dropped by including onion or garlic, as you’ll be able to see at 5:13 in my video. Interestingly, although, in hen, ldl cholesterol oxidation was helped by sage however not garlic. In truth, garlic might even speed up hen fats oxidation. 

So, “there are several measures that can be taken to reduce cholesterol oxidation in foods: reducing the total cholesterol content of foodstuffs by not cooking food with cholesterol-containing fat [like butter or lard], feeding animals with antioxidants, adding antioxidants to food, processing food at low temperatures, using oxygen-excluding packs [opaque vacuum packing, for example], and storing food in the dark.” But, in case you take a step again, you see that solely meals beginning out with ldl cholesterol can find yourself with oxidized ldl cholesterol. So, in phrases of decreasing ldl cholesterol oxidation in meals, the first technique could also be to “reduce the total cholesterol content of the food”—that’s, don’t simply keep away from including additional butter; as a substitute, middle one’s food regimen round complete plant meals, which don’t have any ldl cholesterol to get oxidized within the first place.


  • In the shape of oxysterols, oxidized ldl cholesterol is considered a main set off of Alzheimer’s illness, and ldl cholesterol oxidation merchandise (COPs) have been related to the initiation and development of such main persistent ailments as coronary heart illness, kidney failure, and diabetes.
  • COPs are produced when animal merchandise are heated, and all strategies of cooking can do it, however some are worse than others.
  • Microwaving hen and beef seems to provide about twice as a lot ldl cholesterol oxidation as frying, and grilling appears to be the most secure if the meat is eaten instantly. If leftovers are refrigerated after which reheated in the identical technique, the oxidized levels of cholesterol soar up.
  • Concentrations additionally have a tendency to extend dramatically after publicity to mild and different pro-oxidation brokers, although pink movie (versus clear plastic wrap) blocks some mild waves and will delay ldl cholesterol oxidation.
  • Red meat has extra saturated fats than chicken, however chicken is extra vulnerable to ldl cholesterol oxidation, notably by way of steaming.
  • Dairy and eggs additionally play a job. Ultra-high temperature processing (UHT) of milk makes, for instance, “no refrigeration needed” espresso creamers. UHT seems to spice up oxidized levels of cholesterol by about 50 %, which is bigger than common pasteurization.
  • Egg merchandise in packaged meals, resembling pastas, baked items, and mayonnaise, are additionally problematic.
  • To scale back ldl cholesterol oxidation, the meat business has tried so as to add antioxidants to animal merchandise, resembling lemon balm tea, cherries, and onion, however the easiest way to cut back ldl cholesterol oxidation in meals is by decreasing the whole ldl cholesterol content material in meals—specifically, centering one’s food regimen round complete plant meals that don’t have any ldl cholesterol to start with.

One of the primary triggers of Alzheimer’s illness? Indeed. Check out my video Oxidized Cholesterol as a Cause of Alzheimer’s Disease.

This jogs my memory of Reducing Cancer Risk in Meat-Eaters, my video about reducing publicity to cooked-meat carcinogens referred to as heterocyclic amines.

Other than ldl cholesterol oxidation, are microwaves a good suggestion? See Are Microwaves Safe? and The Effects of Radiation Leaking from Microwave Ovens.

Is unoxidized ldl cholesterol an issue, too? See Cholesterol Crystals May Tear Through Our Artery Lining.

What’s the Flashback Friday: Optimal Cholesterol Level?

Watch the video to search out out! 

Is it simply the small dense ldl cholesterol particles we must be involved about? Check out  Flashback Friday:Does Cholesterol Size Matter?

Want to see by way of egg business propaganda? Check out How the Egg Board Designs Misleading Studies.

You might also be curious about my video Oxidized Cholesterol 27HC May Explain Three Breast Cancer Mysteries.

In well being,

Michael Greger, M.D.

PS: If you haven’t but, you’ll be able to subscribe to my free movies right here and watch my reside displays:

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